Early diagnosis of gastric cancer
Conditions
Interventions
Index test:1. Plasma gene methylation detection
2. Gastrin 17, pepsin I/II, Helicobacter pylori Hp
Sponsors
Nanjing Gulou Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 84 Years
Inclusion criteria
Inclusion criteria: 1. Fully competent, 35~84 years old, regardless of gender. 2. Have or will have gastroscopy and/or pathological examination results at the Centre and agree to provide blood samples.
Exclusion criteria
Exclusion criteria: 1. I have a history of gastric cancer surgery/chemotherapy/radiotherapy. 2. Are pregnant or breastfeeding. 3. Those with severe intellectual disability or language communication impairment, severe heart, brain, lung disease or liver and kidney dysfunction. 4. Have taken demethylating drugs (such as decitabine, azacitidine, hydralazine, procainamide, Procaine, curcumin, etc.). 5. Are receiving or have received radiotherapy, chemotherapy, immunotherapy, or taking antineoplastic drugs (eg, epirubicin, carboplatin, paclitaxel, cisplatin, fluorouracil, capecitabine, tigio, trastuzumab, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma gene methylation;sensitivity;Specificity;accuracy;Kappa consistency; | — |
Countries
China
Contacts
Public ContactXiaoping Zou
Nanjing Gulou Hospital
Outcome results
None listed