Canceled by the investigator. Tou-Tong-Ting decoction therapy for Migraine with Liver Yang Hyperactive syndrome: a single-blinded, randomized controlled trial.

Tou-Tong-Ting decoction therapy for Migraine with Liver Yang Hyperactive syndrome: a single-blinded, randomized controlled trial.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068682

Enrollment

Unknown

Registered

2023-02-27

Start date

2023-03-01

Completion date

Unknown

Last updated

2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Interventions

Control group:Flunarizine Hydrochloride Capsule

Test group:Tou-Tong-Ting decoction

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Conform to the diagnostic criteria of migraine (including migraine with aura and migraine with aura); 2. Conform to the diagnostic criteria of migraine in TCM of Liver Yang Hyperactive syndrome; 3. Age 18-65; 4. Migraine attacks at least once a month in recent three months; 5. Volunteer to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with severe brain, heart, lung, kidney, blood system diseases and malignant tumors; 3. People with infectious diseases, such as viral hepatitis, tuberculosis, AIDS, etc; 4. Migraine secondary to brain and other organic diseases; 5. Special types of migraine, such as hemiplegic migraine, drug dependence migraine, etc.

Design outcomes

Primary

Measure	Time frame
Migraine severity score;TCM syndrome integral of migraine;;	—

Secondary

Measure	Time frame
Migraine Disability Assessment (MIDAS) Test;VAS score;Headache Impact Test (HIT6) ;Migraine-Specific Quality-of-Life Questionnaire (MSQ);Pittsburgh sleep quality index, PSQI;Self-Rating Anxiety Scale, SAS;Self-Rating Depression Scale, SDS;	—

Countries

China

Contacts

Public ContactShaojie Duan

Beijing University of Chinese Medicine

1782802171@qq.com+86 156 5238 6173

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026