Heart failure after PCI in acute myocardial infarction
Conditions
Interventions
Control group:Basic treatment (according to the PCI postoperative guidelines for acute myocardial infarction) + placebo (3 po tid)
Test group:Basic treatment (according to the PCI postoperative guidelines for acute myocardial infarction) + FuFang'DanshenPian(3 po tid)
Sponsors
the First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) patients who meet the diagnostic criteria of acute myocardial infarction; (2) patients aged between 18 and 65, regardless of gender; (3) emergency PCI surgery within 12 hours from onset to admission; (4) patients who voluntarily sign written informed consent.
Exclusion criteria
Exclusion criteria: (1) stable angina pectoris and unstable angina pectoris; (2) Killip grade 4 of acute myocardial infarction; (3) acute myocardial infarction with mechanical complications; (4) severe arrhythmias (such as rapid atrial fibrillation, ventricular tachycardia, high atrioventricular block, etc.); (5) patients with previous history of chronic heart failure or old myocardial infarction. (6) patients with cardiomyopathy, rheumatic heart disease, severe valvular heart disease, pericardial tamponade, acute hypertension, pulmonary hypertension, severe chronic obstructive pulmonary disease or asthma, severe infection, etc. (7) patients with severe liver (ALT >= 3 times the normal upper limit), kidney (Cr >= 265 umol / L), endocrine, hematopoietic system and other primary diseases or mental illness; (8) patients with malignant tumors. (9) allergic constitution, or allergic to a variety of drugs and food, or known to be allergic to the ingredients of compound Danshen tablets; (10) patients who cannot take care of themselves or oral drugs; (11) patients who participate in other clinical studies within three months; (12) patients who are suspected or do have a history of alcohol or drug abuse; (13) pregnant or lactating women; (14) patients with a history of cerebrovascular accidents and major operations and injuries within half a year. (15) patients who need long-term anticoagulation, HAS-BLED bleeding score >= 4, multiple cerebral infarction and cerebral aneurysm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction, LVEF;Minnesota Heart failure scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Syndrome score of traditional Chinese medicine;BNP;hs-CRP;6-minute walking test; | — |
Countries
China
Contacts
Public ContactLuo Chuanjin
the First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed