Ridge preservation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Molars with periodontitis, periodontal–endodontic lesion, endodontic pathology without fistula that could not be preserved; 2.Only one extraction bordered by teeth medially and distally; 3.Four intact bony walls with at least 5mm in height left; 4.Patients who were planning to have implant treatment after tooth extraction; 5.No serious systemic disease, such as bone metabolic and hematologic disorders, uncontrolled diabetes; 6.Patients with sufficient plague control and healthy periodontal maintenance. Bleeding on probing <20%, Plaque index <20% at the time of tooth extraction.
Exclusion criteria
Exclusion criteria: 1.Patients under the age of 18 years or more than 70 years old; 2.Pregnant or lactating women; 3.Acute infection; 4,Smokers of more than 10 cigarettes per day; 5.Patients taking drugs known to affect bone metabolism, such as bisphosphonates, corticosteroids, and nonsteroidal anti-inflammatory drugs, for a long time. 6.If there are multiple eligible sites in a single case, only one tooth site will be selected
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| New bone formation;Material remnants area;nonmineralized connective tissue area;OCN-positive expression area;RUNX-2-positive expression area; | — |
Secondary
| Measure | Time frame |
|---|---|
| buccal plate height;The bucco-lingual/palatal width of alveolar ridge;lingual plate height;The thickness of the buccal bone plate; | — |
Countries
China
Contacts
Stomatological Hospital affiliated to Anhui Medical University