non-alcoholic fatty liver disease (liver stagnation and spleen deficiency combined with dampness syndrome)
Conditions
Interventions
test group:Changju Qinggan Jiangzhi decoction granule
Control group:Changju Qinggan Jiangzhi decoction placebo
Sponsors
Shuguang Hospital affilliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the western medical diagnostic criteria for non-alcoholic fatty liver disease and the TCM syndrome criteria for liver stagnation and spleen deficiency combined with dampness; (2) No history of excessive alcohol consumption (alcohol consumption per week in the past 12 months, < 210 g for men and < 140 g for women); (3) Age of 18-65 years old, both sexes; (4) Not receiving liver-protecting and lipid-lowering drugs in the past 4 weeks; (5) Agree to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Those who are participating in other clinical trials; (2) ALT or AST 5 times higher than the upper limit of normal; (3) Progression to liver cirrhosis or hepatocellular carcinoma; (4) Patients allergic to Cangju Qinggan Jiangzhi decoction; (5) Complicated with serious diseases of vital organs such as heart, brain, lung and kidney; (6) Patients with cancer or psychosis; (7) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the total effective rate of integrate effect;Liver function;blood lipid;Abdominal ultrasound/FibroScan/upper abdominal CT plain scan;TCM syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| body mass index, BMI;Waist to hip ratio, WHR;fasting blood-glucose;fasting insulin;total bile acid;Bile acid profile; | — |
Countries
China
Contacts
Public ContactYang Cheng
Department of Hepatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed