Postoperative delirium
Conditions
Interventions
R group:General anesthesia induction and anesthesia maintenance with remimazolam besylate
P group:General anesthesia induction and anesthesia maintenance with propofol
Sponsors
Zhongda Hospital Southeast University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=65 years; 2. ASA I-IV; 3. patients with a clinical or radiographic diagnosis of a hip fracture (including femoral neck, femoral head, intertrochanteric or subtrochanteric fracture) who are scheduled for elective surgical repair; 4. patients or their principals agree to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients involved in multiple injuries or multiple fractures; 2. Patients with relative contraindications to general anesthesia; 3. Patients with visual, speech, or hearing impairments, neuropsychiatric disorders (including conditions such as dementia that prevent them from cooperating with the evaluation or participating in the trial); 4. Patients with an Edmonton Frailty Reporting Scale (REFS) score of 0-5; 5. Patients who have been enrolled in other clinical studies in the last 3 months; 6. Patients who are considered unsuitable for randomization grouping from health considerations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of post-operative recovery;Postoperative complications;Length of hospital-stay;Intraoperative vital signs/EEG and other indicators;Recovery quality; | — |
Countries
China
Contacts
Public ContactJie Sun
Zhongda Hospital Southeast University
Outcome results
None listed