cerebral arterial stenosis
Conditions
Interventions
Case series:Nil
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. At least one intracranial and/or extracranial artery stenosis (>=30%) confirmed by cervical vascular ultrasound, CTA, MRA, TCD or DSA; 3. Great compliance, agreed to sign informed consent and accept follow-up. Note: Intracranial arteries include: intracranial internal carotid artery (C4-C7 and T segment), middle cerebral artery(M1 and M2), anterior cerebral artery (A1 and A2),posterior cerebral artery (P1 and P2 ), and basilar artery. The extracranial arteries included internal carotid artery C1-C3 and vertebral artery V1-V3 . The internal carotid artery was segmented by Bouthillier method.
Exclusion criteria
Exclusion criteria: 1. ?Suffering from other known serious life threatening diseases (such as hematological diseases, malignant tumors), unstable vital signs or in need of continuous monitoring or in a dying state; 2. Arterial stenosis or occlusion ?by non-atherosclerosis diseases, such as arterial dissection, moya-Moya disease, vasculitis, radioactive vascular disease, or fibromuscular dysplasia; 3. Complicated with intracranial tumor, aneurysm or intracranial arteriovenous malformation; 4. There are risk factors that may lead to cardiogenic embolism, such as atrial fibrillation, left ventricular thrombosis, myocardial infarction within 6 weeks, etc. 5. Those who are pregnant, breast-feeding and planning pregnancy; 6. Patients have been included in other studies that conflict with this study; 7. Other conditions that the investigator considered inappropriate for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characteristics and composition of atherosclerotic plaques in intracranial and/or extracranial arteries;Degree of intracranial/external vascular stenosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;fasting blood glucose;white blood cell count;Red Blood Cell Count;hemoglobin;platelet count;alanine transaminase;aspartate aminotransferase;creatine kinase;total cholesterol;triglyeride;low-density lipoprotein;high-density lipoprotein;creatinine;uric acid; | — |
Countries
China
Contacts
Public ContactBo Hu
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed