Helicobacter pylori infection
Conditions
Interventions
Tailored therapy group:Tailored triple therapy
High dose dual therapy group:HDDT
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients undergoing gastroscopy in the Department of Gastroenterology of our hospital; (2) Patients in need of primary eradication therapy of H.pylori infection; (3) Age 18-75 years old; (4) Male or female. In combination with the routine test conditions and the diagnostic criteria of Helicobacter pylori infection in our hospital, the determination method of H.pylori infection was Warthin-Starry staining and RUT double positive in mucosal biopsy.
Exclusion criteria
Exclusion criteria: (1) Patients who have taken PPI or potassium channel acid blockers (P-CAB) within two weeks before enrollment and those who have taken bismuth or antibiotics within four weeks before enrollment;(2) Patients with malignant tumor of digestive tract; (3) Patients who have undergone gastric or esophageal surgery; (4) Patients with severe basic diseases; (5) Patients who have previously eradicated Helicobacter pylori; (6) Patients who are allergic to the drugs used in this study; (7) Pregnant or lactating women; (8) Patients unwilling to participate or unable to cooperate with this stud
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H.pylori eradicationrate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions;Patient compliace; | — |
Countries
China
Contacts
Public ContactZhiqiang Song
Peking University Third Hospital
Outcome results
None listed