Kidney neoplasms
Conditions
Interventions
ESPB group:Ultrasound-guided erector spinae plane block with local anesthetics (0.7%ropivacaine 10 ml + 1% lidocaine 10 ml) + 5 mg dexamethasone + 0.5 ug/kg dexmedetomidine
Control group:ultrasound-guided erector spinae plane block with 0.9% saline 20 ml
Sponsors
Department of Anesthesiology, Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 18-65 years scheduled for elective laparoscopic nephrectomy; 2) ASA I-III; 3) Willing to participate in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) allergy to local anesthetics; 2) BMI > 35 kg/m2; 3) history of mental illness or taking psychotropic drugs; 4) combined with spinal deformity; 5) long-term use of analgesics or sedatives; 6) history of drug abuse, alcohol or opioid abuse; 7) chronic pain or recent acute pain; 8) severe liver and kidney dysfunction; 9) any reason can not cooperate with the study or researchers think it is not suitable for inclusion in this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the total use of sufentanil during intraoperative period; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraoperative remifentanil consumption;VAS pain scores at rest and coughing at 1 hour, 6 hours, 12 hours, 24 hours, 48 hours after surgery;incidence of nausea and vomiting in the first 24 hour after surgery;times of rescue analgesic; | — |
Countries
China
Contacts
Public ContactMing Yang
Department of Anesthesiology, Second Affiliated Hospital of Army Medical University
Outcome results
None listed