transcutaneous auricular vagus nerve stimulation
Conditions
Interventions
Control group:transcutaneous auricular vagus nerve sham stimulation
Sponsors
Huzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Selected patients, aged 18-65 years old, BMI <= 30 kg/m2, ASA grade I-II, who underwent LC surgery in Huzhou Central Hospital from March, 2023 - June. 2024; No systemic disease or endocrine disease.
Exclusion criteria
Exclusion criteria: Sinus bradycardia; History of abdominal surgery; Take drugs that affect gastrointestinal motility within 1 week before recruitment; Previous gastrointestinal diseases, including peptic ulcer, gastroesophageal reflux disease, hepatobiliary and pancreatic diseases; Allergic to narcotic drugs; Unable to communicate with doctors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting within 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative 48h PONV intensity score greater than 5 points and the incidence of severe PONV;First feeding time;Difference of I-FEED score and incidence of POGD between 24 and 48 hours after operation;Differences of TNF-a, IL-6, IL-1, GAS, MTI and Ach before and after secondary stimulation;NBP, HR, SpO2 values during the use of taVNS instrument;The difference of pain VAS score at 1h, 12h and 24h after surgery;24h after surgery, 48hQoR score difference; | — |
Countries
China
Contacts
Public ContactZhang Ling
Huzhou Central Hospital
Outcome results
None listed