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Feasibility and efficacy of stellate ganglion block for preventing atrial fibrillation after cardiac surgery

Feasibility and efficacy of stellate ganglion block for preventing atrial fibrillation after cardiac surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068572
Enrollment
Unknown
Registered
2023-02-23
Start date
2023-03-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative atrial fibrillation of cardiosurgery

Interventions

Experimental group:Participants received a right-sided ultrasound-guided stellate ganglion block at the C6–C7 level with injection of 7 mL of 0.5% Ropivacaine.
Control group:Participants underwent the same ultrasound-guided procedure at the C6–C7 level with injection of 7 mL of normal saline (sham block).

Sponsors

Sir Run Run Shaw Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. American Society of Anesthesiologists (ASA) grade 1-3; 3. Mitral valve or aortic valve surgery planned under cardiopulmonary bypass, with or without coronary artery bypass grafting; 4. Patients voluntarily participated in this study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. With permanent AF, left or right ventricular assist device implantation; 2. Patients who do not need extracorporeal circulation; 3. Patients who need deep hypothermic circulatory arrest; 4. Patients with active infection or sepsis; 5. The use of immunosuppressive drugs (including the use of steroids) before surgery; 6. Preoperative use of antiarrhythmic drugs (except ß-blockers); 7. Patients with immunodeficiency syndrome; 8. Patients with known neurological diseases; 9. Patients who need to place a central catheter in the left internal jugular vein; 10. Vulnerable groups, including the mentally ill, cognitively impaired, seriously ill, minors, pregnant women, illiterate, etc.

Design outcomes

Primary

MeasureTime frame
the incidence of atrial fibrillation after cardiosurgery;

Secondary

MeasureTime frame
duration of atrial fibrillation after cardiosurgery;C reaction protein;preoperative hemoglobin concentration and postoperative hemoglobin concentration;operation record: operation time, crystalloid infusion volume, blood transfusion volume, intraoperative defibrillation, urine output, duration of respiratory support in the ICU;vital sign: blood pressure and heart rate;Surgical prognosis: pulmonary complications, cardiovascular complications, AKI, and other adverse events.;

Countries

China

Contacts

Public ContactGang Chen

Sir Run Run Shaw Hospital of Zhejiang University School of Medicine

chengang120@hotmail.com+86 137 5711 8681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026