Spontaneous preterm birth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Pregnant women with single child and signed informed consent; ? Pregnant women aged between 18 and 45 years old; ? Pregnant women with cervical insufficiency; ? pregnant women with threatened preterm labor; (5) Pregnant women who received regular medical check-up in our hospital and delivered in our hospital.
Exclusion criteria
Exclusion criteria: ? Pregnant women with infectious diseases; ? Antibiotic/immunosuppressive therapy for pregnant women within one month; ? Pregnant women had sex three days before the test; (4) Pregnant women with serious medical and surgical diseases; (5) Pregnant women received HPV vaccine in the past six months; ? The fetus has serious chromosomal abnormalities or malformations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vaginal microecosystem ;Length of cervical canal; | — |
Secondary
| Measure | Time frame |
|---|---|
| white blood cell count;neonate birth weight; | — |
Countries
China
Contacts
Xiamen Maternal and Child Health Care Hospital affiliated to Xiamen University