Gastrointestinal bleeding
Conditions
Interventions
research group:Ultrahigh pressure angiography was performed after injection of 30mg papaverine hydrochloride
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
12 Years to 100 Years
Inclusion criteria
Inclusion criteria: Gastroscopic examination of patients with upper gastrointestinal bleeding showed that Forrest was rated Ia, Ib, or IIa, and at least one of the following bleeding manifestations occurred again after gastroscopic diagnosis and treatment: (1) The number of hematemesis or black stool is increased, the vomit is bright red or discharge dark red stool or accompanied by active bowel sound; (2) After rapid infusion and blood transfusion, peripheral circulatory failure showed no obvious improvement or worsened after temporary improvement, the central venous pressure still fluctuated slightly stable and then declined again; ? Red blood cell count, hemoglobin concentration and hematocrit continued to decrease, while reticulocyte count continued to increase; (4) Blood urea nitrogen increased continuously or again under the condition of sufficient fluid and urine volume; (5) More new blood was extracted from gastric tube; (6)Active bleeding was found to be unable to stop bleeding under endoscopy. These patients underwent routine hypertensive angiography and were enrolled in the study if the angiography was negative
Exclusion criteria
Exclusion criteria: ? Pregnant or lactating patients; ? the dying patient; ? Patients with advanced malignant disease or other advanced malignant disease with limited life expectancy; ? Patients who are allergic to contrast agent or papaverine hydrochloride; ? Patients who could not cooperate with or refused interventional treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive rate of angiography; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complication rates;Rebleeding rate; | — |
Countries
china
Contacts
Public Contactzhongjiawei
The First Affiliated Hospital of Nanchang University
Outcome results
None listed