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Association of high AMH during pregnancy with IVF pregnancy outcomes in infertile patients: a prospective observational cohort study

Association of high AMH during pregnancy with IVF pregnancy outcomes in infertile patients: a prospective observational cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068554
Enrollment
Unknown
Registered
2023-02-23
Start date
2023-03-24
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Observational group:None
Control group:None

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with PCOS underwent IVF/ICSI and obtained clinical pregnancy: According to the Rotterdam criteria in 2003, if two of the following three criteria are met, and other diseases that cause similar clinical manifestations are excluded, the diagnosis can be made: (1) Androgen (excessive clinical or/and biochemical manifestations); (2) Occurrence of ovulation or anovulation; (3) Polycystic changes in the ovary: the volume of unilateral ovary increases by more than 10ml (excluding cysts and dominant follicles) or there are more than 12 follicles with a diameter of 2-9mm in unilateral ovary; 2. Normal response to IVF/ICSI population and clinical pregnancy: IVF/ICSI due to male factors or fallopian tube factors; 3. Over 18 years old; 4. Single pregnancy.

Exclusion criteria

Exclusion criteria: 1. Aged over 40 years old; 2. Patients with recurrent miscarriage, that is, patients with >= 2 consecutive miscarriages before 20 weeks of pregnancy; 3. Other endocrine diseases that lead to clinical manifestations similar to PCOS, such as hyperprolactinemia, Cushing’s syndrome, congenital adrenal hyperplasia, etc.; 4. Patients with PGT.

Design outcomes

Primary

MeasureTime frame
Premature birth;

Secondary

MeasureTime frame
Early abortion rate;Late abortion rate;Clinical pregnancy rate;Live birth rate;Pregnancy and perinatal complications;Birth weight;Congenital abnormalities;Other adverse events;

Countries

China

Contacts

Public ContactLi Rong

Peking University Third Hospital

roseli001@sina.com+86 137 0108 5402

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026