Microvascular angina pectoris with anxiety and depression
Conditions
Interventions
control group:Shexiang Baoxin Pill Simulant+Western medicine treatment
Test group:Shexiang Baoxin Pill+western medicine treatment
Sponsors
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) It meets the diagnostic criteria of microvascular angina pectoris in western medicine; (2) Meet the diagnostic criteria for anxiety, 5 points = GAD-7 score = 14 points; (3) Meet the diagnostic criteria for depression, 5 points = PHQ-9 score = 14 points; (4) Conforming to the above diagnostic criteria of Qi stagnation and blood stasis syndrome; (5) Age: 20-75 years old, male or female; (6) Subjects were informed and voluntarily signed the informed consent form. Compliance with (1), (2) or (3) and (4)~(6) can be included
Exclusion criteria
Exclusion criteria: (1) Have obvious liver and kidney diseases, or ALT and AST are 1.5 times higher than the upper limit of normal, and Cr and BUN are higher than the upper limit of normal; (2) Patients with severe heart failure, myocardial disease, structural heart disease, uncontrolled hypertension and other serious cardiovascular diseases; (3) Patients with serious mental illness, hematopoietic system disease, malignant tumor and other major diseases; (4) Patients who have taken anti-anxiety and depression drugs for a long time or within a week; (5) Have serious suicidal tendencies; (6) Pregnant or pregnant women, lactating women; (7) Those who have participated or are participating in other clinical research in the past three months; (8) Suspicious or definite allergy to the study drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seattle Angina Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome score;Generalized anxiety scale;Inflammatory factor;Anti-inflammatory factor;Vascular endothelial injury markers;Peripheral blood neurotransmitter; | — |
Countries
China
Contacts
Public ContactLong linzi
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Outcome results
None listed