postoperative delirium
Conditions
Interventions
Experimental group:Cerebral oxygen saturation monitoring adjusts anesthesia protocols
Control group:Maintain MAP 60-100 mmHg
Sponsors
Fuwai Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: Age = 65 years old; Patients undergoing coronary artery bypass grafting without cardiopulmonary bypass; Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary surgery and emergency surgery; 2. Patients with combined surgery such as simultaneous CABG mixed percutaneous coronary intervention; 3. Previous history of schizophrenia, epilepsy, Parkinson's disease, myasthenia gravis or severe dementia (severe cognitive dysfunction based on Mini-Mental State Examination score < 24 points); 4. Unable to communicate because of language barriers; 5. Previous history of brain trauma or neurosurgery; 6. Left ventricular ejection fraction (EF) < 30%; 7. Severe carotid stenosis, hepatic and renal insufficiency or other cardio-pulmonary and cerebral diseases diagnosed by clinical diagnosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative renal insufficiency;Incidence of postoperative myocardial infarction;postoperative length of Hospital Stay;Length of ICU stay; | — |
Countries
China
Contacts
Public ContactTian Lijuan
Fuwai Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed