Porto-sinusoidal vascular disorder
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18 to 75 years; 2. Diagnosed PSVD based on clinical manifestations, laboratory and imaging examinations and liver histopathological biopsy.
Exclusion criteria
Exclusion criteria: 1. Diagnosed liver cirrhosis or other non-cirrhotic portal hypertension diseases(such as congenital hepatic fibrosis, Budd-chiari syndrome, sinusoidal obstruction syndrome) based on histopathological biopsy; 2. Previous TIPS or surgical shunt; 3. With other complications related to portal hypertension(such as refractory ascites, hepatorenal syndrome and hepetopulmonary syndrome); 4. Child-Pugh score is greater than 12; 5. Uncontrolled EGVB or stabilized for less than one week; 6. With infection before operation; 7. Recurrent attacks of hepatic encephalopathy(more than 2 times); 8. Dysfunction of organs including heart, lung, kidney and brain, and pulmonary hypertension; 9. Liver cancer and other malignant tumors beyond Milan criteria; 10. Pregnant and lactating women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complications related to portal hypertension;Blood biochemical indices;Hepatic encephalopathy;Refractory ascites;Infections;Liver failure; | — |
Countries
China
Contacts
West China Hospital, Sichuan University