Premalignant oral epithelial lesions
Conditions
Interventions
treatment group:treatment with cinobufacini
Sponsors
The School of Stomatology, the Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years old (including 18 and 75 years old), gender is not limited, autonomous individuals who can cooperate with treatment; 2. Abnormal hyperplasia was confirmed by pathological examination, but no definite canceration was found, and oral mucosal lesions with a diameter of at least 1 cm; 3. Agree to participate in this experiment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Oral cancer surgery within half a year; 2. Uncontrolled cardiovascular disease, blood disease, acute infectious disease, diabetes and other systemic diseases; 3. Have a history of severe drug allergy; 4. Patients who use other drugs for the treatment of oral mucosal diseases at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathology evaluation;Numeric rating scales;Activity score;DNA Ploidy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lesion area;Toxicity;Recurrence rate; | — |
Countries
China
Contacts
Public ContactWang Xinwen
The School of Stomatology, the Fourth Military Medical University
Outcome results
None listed