Perioperative analgesia and sedation
Conditions
Interventions
Young and middle-aged childless group:Different doses of Nalbuphine
Young and middle-aged childbearing group:Different doses of Nalbuphine
Elderly group:Different doses of Nalbuphin
Sponsors
Shaanxi Provincial People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? Age: 18-85; ?BMI18.5-27.9 ? ASA classification: Class I - II; ? Patients who are scheduled to undergo hysteroscopy; ? Volunteered to participate in this study, and was informed in detail and signed the informed consent form
Exclusion criteria
Exclusion criteria: ? Patients with severe anemia; ? Patients with severe hypertension (systolic blood pressure>180mmHg, and/or diastolic blood pressure>110mmHg); Patients with pulmonary infection and asthma history; ? Patients with neurological and psychiatric diseases; ? Patients with hyperthyroidism and hypothyroidism; ? Those who cannot communicate or cooperate; ? Allergic or addicted to the drugs related to the study; ? Complicated with severe heart, lung, liver and kidney diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative limb activity rate;Incidence of respiratory depression;Incidence of adverse reactions such as dizziness, nausea and vomiting after operation;Incidence of postoperative abdominal pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;blood pressure;Blood oxygen saturation;eyelash reflex disappears;Postoperative recovery time;Operation completion time;Total dosage of propofol;Analgesic effect (measured by NRS scale);Sedative effect (measured by Ramsay scale);Postoperative recovery of consciousness and movement (measured by 4CRT test); | — |
Countries
China
Contacts
Public ContactCao Yuan
Shaanxi Provincial People's Hospital
Outcome results
None listed