Sepsis and Multiple Sclerosis
Conditions
Interventions
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. The age of the patient is >= 18 years old; 2. Admission = 2 points): determination of infection focus: clear infection focus such as respiratory tract infection, urinary tract infection, intestinal infection, etc., and exclude central nervous system infection focus ; 4. Clinically diagnosed patients with multiple sclerosis who meet the clinical diagnostic criteria for multiple sclerosis; 5. Patients and their families have informed consent to participate in the research project; 6. Be able to communicate briefly with researchers and complete the evaluation of relevant scales.
Exclusion criteria
Exclusion criteria: 1. Patients with primary central nervous system diseases (such as cerebral hemorrhage, cerebral infarction, brain trauma, etc.); 2. Patients have previously suffered from mental or neurological diseases (for example, intracranial tumors); 3. There is clear evidence of encephalitis/meningitis; 4. Disturbance of consciousness and changes in mental state caused by acute encephalopathy caused by other reasons. Including metabolic encephalopathy, blood electrolyte disturbance, toxic encephalopathy, primary central nervous system disease, and sedative and hypnotic drug interference, etc.; 5. Antibiotics, hormones and other immunosuppressive drugs were used before admission; 6. Renal replacement therapy such as hemofiltration and hemodialysis; 7. Tumors, autoimmune diseases, liver cirrhosis, uremia, etc.; 8. Recent history of blood transfusion; 9. Patients or family members refuse to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokine;chemokine protein;core gene mRNA and other levels; | — |
Countries
China
Contacts
Public ContactLi Gong
The Third Xiangya Hospital of Central South University
Outcome results
None listed