Comparison of anesthesia effects of desflurane and sevoflurane combined with propofol in scoliosis patients

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068499

Enrollment

Unknown

Registered

2023-02-21

Start date

2023-02-21

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scoliosis patients

Interventions

Experimental group:Propofol combined with desflurane inhalation

control group:Propofol combined with sevoflurane inhalation

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: (1) The patient was 18-50 years old, with ASA grade of ? - ?. The clinical diagnosis was scoliosis and kyphosis; (2) : No contraindication of anesthesia; (3) No serious cardiopulmonary dysfunction, liver, kidney and muscle system abnormalities; (4) Mental examination is normal; (5) Not taking analgesic or sedative drugs for a long time; (6) Blood pressure is normal.

Exclusion criteria

Exclusion criteria: (1) Idiopathic scoliosis; (2) Patients with scoliosis should not use inhaled anesthetics; (3) The patient cannot cooperate; (4) If the patient is unable to remove the endotracheal tube, he/she should be sent to ICU for treatment.

Design outcomes

Primary

Measure	Time frame
Pipe pulling time;Anesthesia time;Eye-opening time;Operation time;	—

Secondary

Measure	Time frame
Alert/sedation score (OAA/S);heart rate;blood pressure;Perioperative adverse reactions;	—

Countries

China

Contacts

Public ContactLiu Siyuan

Nuclear Industry 416 Hospital

31820463@qq.com17381805450

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026