Helicobacter pylori infection
Conditions
Interventions
research group:Vonolaxan 20mg bid + amoxicillin 500mg tid for 14 days
control group:Omeprazole 20mg bid + colloidal bismuth pectin 200 mg bid + amoxicillin 1000mg bid + clarithromycin 500mg bid for 14 days
Sponsors
The Sixth Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Healthy people with positive 13C-urea breath test, aged 18-70 years; 2. Consistent with the indications for Helicobacter pylori eradication (according to the Fifth National Consensus Report on the Management of Helicobacter pylori Infection).
Exclusion criteria
Exclusion criteria: 1. History of Hp eradication treatment; 2. History of esophageal or gastric surgery; 3. Patients with peptic ulcer, gastrointestinal bleeding, gastric cancer or gastric MALT lymphoma; 4. Antibiotics, bismuth and traditional Chinese medicine containing antibacterial activity were taken 4 weeks before treatment, and voronaxan, PPI, H2 receptor antagonist and other drugs were taken 2 weeks before treatment; 5. Severe heart, lung, kidney, liver dysfunction, low immunity; 6. Patients during pregnancy and lactation; 7. People with mental diseases and communication disorders; 8. Patients who are allergic to the drugs used in the eradication program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rate of Hp; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactPeng Tieli
The Sixth Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed