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Diagnostic value of serum adenosine deaminase and a-hydroxybutyrate dehydrogenase in scrub typhus

Diagnostic value of serum adenosine deaminase and a-hydroxybutyrate dehydrogenase in scrub typhus

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068470
Enrollment
Unknown
Registered
2023-02-20
Start date
2023-02-20
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

scrub typhus

Interventions

Gold Standard:According to the diagnostic criteria of the Technical Guidelines for scrub typhus Prevention and Control (Trial) issued by the China Center for Disease Control and Prevention in 2009 (ZJ
Index test:serum adenosine deaminase,a-hydroxybutyrate dehydrogenase, liver function, renal function, C-reactive protein and blood cell count.

Sponsors

The Fourth Affiliated Hospital of Guangxi Medical University(Liuzhou Workers' Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. With fever symptoms, axillary temperature>37.5 ? is measured at least once within 24 hours; 3. There was a history of field activities within 3 weeks before the onset of disease, such as field work, fishing, camping, sitting and lying on grass, contact and use of straw.

Exclusion criteria

Exclusion criteria: 1. Pregnancy; 2. Those with severe basic diseases, such as cardiac function grade IV, post-stroke paralysis, uremia and decompensation of liver cirrhosis; 3. Those with acute serious cardio-cerebrovascular diseases, such as acute myocardial infarction, malignant arrhythmia, stroke and epilepsy; 4. Tumor patients; 5. Patients with autoimmune diseases or organ transplantation need long-term use of immunosuppressive agents or adrenocortical hormones; 6. Poor compliance, unable to cooperate with diagnosis, treatment and follow-up.

Design outcomes

Primary

MeasureTime frame
serum adenosine deaminase;C-reactive protein;

Secondary

MeasureTime frame
a-hydroxybutyrate dehydrogenase;liver function;renal function;blood cell count;

Countries

China

Contacts

Public ContactLi Laodong

The Fourth Affiliated Hospital of Guangxi Medical University(Liuzhou Workers' Hospital)

lilaodong@qq.com+86 18377281867

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026