Hp infection
Conditions
Interventions
Gold Standard:C13 breath test, histopathological diagnosis
Index test:Saliva or urine nucleic acid test for Hp
Sponsors
Ruijin Hospital Shangai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria of helicobacter pylori group :(1) Children diagnosed with helicobacter pylori infection according to the expert consensus on the diagnosis and treatment of helicobacter pylori infection in children; (2) Under the age of 14, both male and female; (3) Children who need endoscopy as determined by the clinician; (4) No contraindications of endoscopic examination; (5) Sign the informed letter. 2. Inclusion criteria of the control group :(1) Children who were not diagnosed with helicobacter pylori infection and were determined by clinicians to come to the hospital for endoscopy; (2) Under 14 years of age; (3) Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who could not complete endoscopy: (1) patients with severe heart disease such as arrhythmias, active heart infarction, and severe heart failure; (2) Severe lung diseases: asthma, respiratory failure, unable to lie flat; (3) Patients with severe hypertension, mental illness and obvious disturbance of consciousness cannot cooperate; (4) Acute perforation of esophagus, stomach and duodenum; (5) Severe acute intestinal infection; (6) Patients with coagulopathy and bleeding tendency; (7) Severe spinal deformity; 2. H2 receptor antagonists or PPI inhibitors were used within 2 weeks before the study, and antibiotics and bismuth were used within 4 weeks; 3. Refusal or failure to perform endoscopy or biopsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nucleic acid of Hp;C13 breath test;histopathological test for Hp;susceptibility;Specificity;accuracy; | — |
Countries
China
Contacts
Public ContactChundi Xu
Ruijin Hospital Shangai Jiaotong University School of Medicine
Outcome results
None listed