Gynecological endoscopic surgery
Conditions
Interventions
Traditional opioid group (Group O):Propofol 1.5-2mg/kg, Sufentanil 0.5µg/kg and rocuronium 0.6 mg/kg were used for induction,Propofol 2-12mg/kg/h+ Remifentanil 2-4ug/kg/h for maintenance,Postoperative
Continuous epidural anesthesia without opioids (GS group):Epidural puncture anesthesia was performed with 0.5% ropivacaine 5ml, followed by induction with propofol 1.5-2mg/kg and rocuronium 0.6 mg/kg.
No opioid general anesthesia group (OF group):Propofol 1.5-2mg/kg, rocuronium bromide 0.6 mg/kg and lidocaine 1mg/kg were used for induction.TAP was then performed using 0.25% ropivacaine 20ml.Mainten
Sponsors
The First Affiliated Hospital of University of South China
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.ASA Grade I-III, female patients aged 25-65 years; 2. No mental disorders, mental disorders and other diseases 3. Body mass index: 15-32kg/m^2; 4. An elective gynecological laparoscopic hysterectomy is planned, which is expected to last 1-3 hours; 5. No history of drug abuse, drug abuse or alcohol abuse; 6. There is no contraindication of intraspinal anesthesia; 7. Can understand the purpose of the study, participate in the study voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. ASA III level or above; 2. Have serious mental illness; 3. Emergency operation; 4. Patients with poorly controlled or untreated hypertension (blood pressure above 160/100mmHg); 5. Patients with serious heart disease; 6. Combined organ resection is required; 7. Untreated and ineffective patients with hyperthyroidism; 8. Recently participated in other clinical studies. 9. Those that the researchers considered unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;Systolic blood pressure;Diastolic blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug use during surgery;Adverse reaction after operation; | — |
Countries
China
Contacts
Public ContactXiaoling Hu
The First Affiliated Hospital of University of South China
Outcome results
None listed