neonatal sedation
Conditions
Interventions
Drug Group :Oral chloral hydrate 50mg/kg
Control Group:no
Sponsors
Wenling Matemal and Child Health Care Hospital, Zhejiang, China
Eligibility
Sex/Gender
All
Age
1 Years to 1 Years
Inclusion criteria
Inclusion criteria: 1. The birth weight > 2000g,singleton, the gestational age >35 weeks; 2. TSB within 7 days < the 95% percentile of Bhutani's hourly bilirubin nomogram, BAEP examination is performed on the 7th to 14th day of birth.
Exclusion criteria
Exclusion criteria: 1. Twins or multiple; 2. Suffocation rescuers (Apgar score 1 min 0~4 points or 5 min 0~6 points); 3. Neonatal genetic metabolic disease or glucose-6-phosphate dehydrogenase deficiency; 4. Hypoxemia or mechanical ventilation for more than 5 days; 5. Have a family history of permanent hearing impairment and intrauterine infection caused by cytomegalovirus, rubella virus, herpes virus, syphilis or toxoplasma gondii; 6. Craniofacial deformities, including auricle and auditory canal deformities; 7. The mother used ototoxic drugs during pregnancy; 8. Suffering from bacterial meningitis; 9. Syndromes or Genetic diseases related to hearing impairment; 10. TSB>342µmol/L within 7 days of birth; 11. The clinical data are unreliable or incomplete, and the parents refuse to treat, automatically discharge, and die; 12. Children with contraindications of chloral hydrate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wave VI of BAEP;latency of VI wave; | — |
Countries
China
Contacts
Public ContactZhimin Sheng
Wenling Matemal and Child Health Care Hospital, Zhejiang, China
Outcome results
None listed