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Transcranial alternating current stimulation (tACS) in the treatment of depression and improvement of cognitive function: clinical randomized controlled study

Transcranial alternating current stimulation (tACS) in the treatment of depression and improvement of cognitive function: clinical randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068379
Enrollment
Unknown
Registered
2023-02-16
Start date
2023-02-17
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

tACS (Transcranial alternating current stimulation) group :
Sham rTMS group :
Control group :None

Sponsors

Ningbo Kangning Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for depression in the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (International Classification of Diseases, ICD-10); 2. Aged 18 to 65 years; 3. Right-handed; 4. The Ethics Committee of the Municipal Psychiatric Hospital agreed, and the subjects signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe physical diseases, infectious diseases and immune system diseases; 2. Patients with severe neurological disease, mental retardation or organic brain disease; 3. Pregnant or lactating women; 4. Those who received electroconvulsive therapy within the past 3 months; 5. Have a history of epileptic seizures; 6. Those who are not suitable to receive rTMS or tDCS treatment after evaluation, and those who cannot complete the collection of relevant indicators.

Design outcomes

Primary

MeasureTime frame
HAMD (Hamilton Depression Rating Scale) score;HAMA (Hamilton Rating Scale Anxiety) score;PSQI (Pittsburgh Sleep Quality Index) score;RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) score;TMS-MEP (Transcranial Magnetic Stimulation Motor Evoked Potentials);TMS-EEG(Transcranial Magnetic Stimulation Electroencephalogram);fNlRs (Functional Near-Infrared Spectroscopy);rs-EEG (resting-state Electroencephalogram); ERP (Event Related Potentials);

Countries

China

Contacts

Public ContactLi Xingxing

Ningbo Kangning Hospital

290534201@qq.com13857476641

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026