Gastrointestinal Tumor
Conditions
Interventions
Test group:Obtain puncture tissue and conduct organoid drug sensitivity test
Database building group:Obtain puncture tissue and conduct organoid
Sponsors
Beijing Friendship Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients with gastrointestinal tumors confirmed by pathology and imaging; 2) The clinical manifestations are the following two types of multi-node samples: a. patients with gastric cancer who have received radical surgery and are currently in remission but have a certain risk of recurrence; b. patients with advanced gastric cancer receiving drug treatment; 3) Complete clinicopathological and follow-up data; 4) The patient voluntarily joins the study and signs the informed consent form, with good compliance and cooperation in follow-up; 5) 18-75-year-old; patients with good general condition can tolerate chemotherapy and targeted treatment;
Exclusion criteria
Exclusion criteria: 1) Failure to comply with the research protocol or research procedure; 2) Have a history of other malignant tumors in the last 5 years; 3) Any unstable systemic disease, including uncontrolled hypertension, unstable angina pectoris, angina pectoris that has begun to attack within the last three months, congestive heart failure (=NYHA Level II), myocardial infarction within six months, serious arrhythmia requiring drug treatment, liver, kidney or metabolic disease); 4) Uncontrolled infection; 5) Patients with mental illness; 6) The researcher believes other conditions that are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease free survival;Progression free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Countries
China
Contacts
Public ContactZhigang Bai
Beijing Friendship Hospital,Capital Medical University
Outcome results
None listed