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Clinical study of Gubiao Fanggan granule in the treatment of lung-spleen qi deficiency syndrome during the recovery period of COVID-19.

Clinical study of Gubiao Fanggan granule in the treatment of lung-spleen qi deficiency syndrome during the recovery period of COVID-19.

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068358
Enrollment
Unknown
Registered
2023-02-16
Start date
2023-02-16
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Gubiao Fanggan group:Gubiao Fanggan granule was taken orally, 1 package each time, 2 times a day. One course of treatment and observation was 1 course. According to the patient's condition, external t
Control group:Western medicine was used for symptomatic and supportive treatment (such as atomization, phlegm elimination, balance of water and electrolyte, etc.), and external treatment of traditiona

Sponsors

Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) When the condition of the COVID-19 infected patient is significantly improved, the vital signs are stable, the body temperature is normal for more than 24 hours, and the patient's lung imaging reexamination shows that the acute exudative lesions are significantly improved, the patient may enter the recovery period. (2) The patient was diagnosed as a recovery period syndrome of lung-spleen qi deficiency syndrome. (3) Physical performance score (PS) =2; (4) predicted survival time =3 months; (5) Both sexes, aged 18-75 years old.

Exclusion criteria

Exclusion criteria: (1) Severe and critical cases of COVID-19 infected patients, and TCM syndrome types in the convalescence period belong to patients with deficiency of Qi and Yin and syndrome of cold drink suppressing lung. (2) Patients with other serious organic diseases; (3) participants in other drug trials; (4) immune diseases, allergic constitution, mental disorders; (5) pregnancy, lactation period.

Design outcomes

Primary

MeasureTime frame
Clinical improvement;Physical condition;

Secondary

MeasureTime frame
Duration of survival;MMRC dyspnea score;The 6-minute walk test was performed;IgA Antibodies;lymphocytes;The 3-month relapse rate;Status of Immunity;Toxic side effects;

Countries

China

Contacts

Public ContactLiu Fang

Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine

ZengWen@stu.hnucm.edu.cn15073126326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026