Changes of metabonomic profile of venous blood of spermatic cord in patients with varicocele and its clinical significance

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300068353

Enrollment

Unknown

Registered

2023-02-16

Start date

2022-08-24

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

varicocele

Interventions

Venous blood of spermatic cord in patients with varicocele:No

Peripheral blood of patients with varicocele:No

Eligibility

Sex/Gender

Male

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with primary varicocele met the Guidelines for Diagnosis and Treatment of varicocele formulated by the Chinese Medical Association in 2015, and met the following criteria: ? Aged 18-40; ? there is a sound semen quality analysis report and other clinical information ? need surgery for treatment;

Exclusion criteria

Exclusion criteria: ? testicular cancer; ? testicular atrophy; ? Epididymal orchitis; (4) undescended testicles; ? Other known genetic, endocrine, infection and other diseases that may affect semen quality. ? Secondary or no surgical indications of varicocele; ? Unable to obtain informed consent, refused to participate in the researcher

Design outcomes

Primary

Measure	Time frame
metabolite differences in blood;	—

Secondary

Measure	Time frame
Semen PH;sperm count;sperm motility;sperm survival rate;sperm malformation rate;	—

Countries

China

Contacts

Public ContactCi Zou

The Second Affiliated Hospital of Anhui Medical University

zci2003@qq.com13515669967

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026