glaucoma
Conditions
Interventions
Sponsors
PLA Army Characteristic Medical Center
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of experimental group 1) Primary angle-closure glaucoma: according to the international society of geographical and epidemiologic ophthalmology (ISGEO) diagnostic criteria. 2) Primary open angle glaucoma (POAG): patients with open angle (at least Shaffer III), glaucoma visual field defects, and at least one eye's typical cup to disc ratio (CDR)>0.6. 3) At least 50 years old and willing to sign the informed consent form, and willing to provide medical record data according to the specified data collection content; 4) There was no other eye disease and no history of internal eye surgery except primary glaucoma and cataract before operation. Inclusion criteria of the control group: 1) There is age-related cataract with opaque lens, which is matched with the age (± 5 years old) and sex of the glaucoma group. There is no increase in intraocular pressure (intraocular pressure<21 mmHg) at present or in the past, and no drugs have been used to reduce intraocular pressure before. The cup-to-disc ratio is<0.4 and the difference between the cup-to-disc ratio of both eyes is<0.2. There is no family history of glaucoma and no local drug treatment. 2) There was no other eye disease and no history of internal eye surgery except for age-related cataract before operation. 3) At least 50 years old and willing to sign the informed consent form, and willing to provide medical record data according to the specified data collection content.
Exclusion criteria
Exclusion criteria: Exclusion criteria of the experimental group: 1) Other ophthalmic diseases (including but not limited to central retinal vein occlusion, uveitis, age-related macular degeneration, high myopia and retinitis pigmentosa) or other serious diseases such as intraocular surgery, diabetes history, immune diseases, other metabolic diseases, systemic diseases and malignant tumors were excluded. 2) Patients with any type of neurosurgery history, brain tumor, epilepsy, stroke, traumatic brain injury and other diseases. 3) Patients who cannot be examined for systemic diseases that affect the eye condition. Exclusion criteria for the control group: 1) serious diseases such as diabetes history, other metabolic diseases, systemic diseases and malignant tumors, patients with any type of neurosurgical history, brain tumors, epilepsy, stroke, traumatic brain injury and other diseases. 2) Patients who cannot be examined for systemic diseases that affect the eye condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood glucose levels under fasting state;Fasting insulin;Glucose-6-phosphate dehydrogenase;Transketolase;NADP/NADPH;lactic acid;lactate dehydrogenase;Pyruvate kinase; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment;Mini-Mental State Examination;the Digit Span Test; | — |
Countries
China
Contacts
Public ContactLing Yu
PLA Army Characteristic Medical Center
Outcome results
None listed