ulcerative colitis
Conditions
Interventions
Test group:Jianpi-Qingchang decoction+Mesalazine
Sponsors
Shanghai Traditional Chinese MedicineIntegrated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-70 years, both sexes. (2) All patients were diagnosed with ulcerative colitis by e-colonoscopy and pathology, and the diagnosis was in accordance with the criteria established in the Consensus Opinion on the Diagnosis and Treatment of Inflammatory Bowel Disease (Beijing, 2018) . (3) Meet the criteria for the identification of spleen deficiency and damp-heat evidence in Chinese medicine in the 2018 Guidelines for the Treatment of Ulcerative Colitis, a Common Disease of the Digestive System . (4) Have had a colonoscopy within the last 1 year. (5) No serious heart, liver, kidney or other important organ and hematologic disorders. (6) The patient fully understands the purpose and content of the test, has good compliance, and voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Have participated in other clinical trials within the last 6 months. (2) Have taken antibiotics within the last 3 months. (3) Within the last 4 weeks have used immunosuppressive agents, biological agents, other non-steroidal (steroidal) anti-inflammatory drugs, the gastrointestinal mucosal protective agents, intestinal probiotics, prebiotic preparations. (4) The presence of liver and kidney insufficiency (test indicators exceeding the upper limit of 2 times). (5) Women during lactation and pregnancy. (6) Gastric and duodenal ulcers, history of intestinal surgery, intestinal obstruction, intestinal perforation, perianal abscess, severe bleeding disorders, tumors. (7) Patients with mental illness, unable to control themselves or who do not have autonomy (8) Patients who do not have legal capacity or whose legal capacity is limited (9) Patients with a history of other medical conditions that, in the investigator's assessment, may interfere with the results of the trial or increase patient risk. (10) Any other condition that, in the opinion of the investigator, makes participation in the study inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue Scale,FS-14;Disease activity index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory Bowel Disease Questionnaire, IBDQ;Evaluation criteria for curative effect of TCM symptoms; | — |
Countries
China
Contacts
Public ContactDai yan cheng
Shanghai Traditional Chinese Medicine Integrated Hospital
Outcome results
None listed