A randomized, controlled, multicenter clinical study on the effect of acupuncture-drug combination therapy based on the theory of

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068334

Enrollment

Unknown

Registered

2023-02-15

Start date

2023-02-07

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe pneumonia

Interventions

test group:Give the standard treatment and nursing care for severe pneumonia patients with invasive mechanical ventilation, and decoction and acupuncture based on the theory of "reinforcing earth to g

control group:Give the standard treatment and nursing care for severe pneumonia patients with invasive mechanical ventilation ,and the same amount of decoction based on the theory of "reinforcing eart

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: ?Age over 18 years old ?The duration of invasive mechanical ventilation is greater than 96h ?Meet the above diagnostic criteria for pneumonia, severe pneumonia, and difficult-to-wean ?Meet the diagnostic criteria for dual deficiency of the lung-spleen pattern in traditional Chinese medicine ? Obtain the consent of the subjects or their family members.

Exclusion criteria

Exclusion criteria: ?Currently undergoing extracorporeal membrane oxygenation ?Pregnancy or breastfeeding status ?Pleural effusion occupying more than one-third of the pleural cavity on both sides ?Neuromuscular disease that may affect the respiratory muscles ?Congenital heart disease history ? Obvious congestive heart failure ? Failure to wean due to current hypervolemia ? Pneumothorax, flail chest ? Body mass index = 40kg/m2 ? Subdiaphragmatic infection, known or suspected phrenic nerve paralysis ?Bacteremia (within 48 hours of negative blood culture) ?Current hemodynamic instability (requiring vasopressors), sepsis or septic shock ?Participating in other clinical trials related to mechanical ventilation weaning ?The patient may not be able to continue further treatment in the hospital due to various non-medical reasons ?The patient has no indwelling gastric tube and cannot feed traditional Chinese medicine through the nose ?The patient cannot cooperate with acupuncture due to restlessness and other reasons.

Design outcomes

Primary

Measure	Time frame
mechanical ventilation time;30-day weaning success rate;	—

Secondary

Measure	Time frame
TCM Syndrome Score;Diaphragm function;	—

Countries

China

Contacts

Public ContactChanglong Wei

The Second Affiliated Hospital of Zhejiang Chinese Medical University

weicltcm@163.com15157112380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026