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Effects of different oxygen concentration on postoperative pulmonary function in patients undergoing radical prostatectomy

Effects of different concentrations of inhaled oxygen on postoperative pulmonary function and pulmonary complications in elderly patients undergoing radical prostatectomy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068328
Enrollment
Unknown
Registered
2023-02-15
Start date
2023-02-15
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer

Interventions

Low Fio2 group:30%Fio2
High Fio2 group:80%Fio2

Sponsors

The second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1) age =65 years, body mass index 18.5-28 kg/m ~ 2, Asa Grade II or III 2) there was no obvious abnormality in pulmonary function, no deformity of spine or thorax, no difficult airway, asthma or COPD 3) the estimated operation time was =2 hours 4) volunteer and sign the informed consent form

Exclusion criteria

Exclusion criteria: 1) body mass index (BMI) less than 18.5 kg/m2 or more than 28 kg/m2; 2) COPD patients; 3) the pulmonary function suggested moderate or above obstructive/restrictive ventilatory dysfunction; 4) preoperative arterial partial pressure of oxygen less than 60mmHg; 5) predicted difficult airway; 6) coronary artery disease; 7) patients with previous artificial pacemaker or defibrillator implantation; 8) patients using other bioimpedance devices at the same time; 9) patients with wound, dressings or infection focus near the electrode bandage; 10) patients with spinal lesions. 11) other researchers consider it inappropriate to participate in the stud

Design outcomes

Primary

MeasureTime frame
EIT ventilation distribution results;

Secondary

MeasureTime frame
Pulmonary function was measured preoperatively and 1,3,5 days postoperatively;Postoperative pulmonary complications occurred 1,3,5 days after operation;arterial blood gas analysis;Markers of oxidative stress;Respiratory Mechanics Index;Hemodynamics indicators;PONV;Length of hospital stay;

Countries

China

Contacts

Public ContactYun Li

The second Affiliated Hospital of Anhui Medical University

yunli_001@aliyun.com15105517565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026