urologic surgery
Conditions
Interventions
Group A:mivacurium (0.15 mg.kg-1)
Group B:mivacurium (0.20 mg.kg-1)
Group C:mivacurium (0.25 mg.kg-1)
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 3–12 years; 2. American Society of Anesthesiologists (ASA) physical status I to II; 3. No abnormalities in laboratory and imaging examinations before operation; 4. Children's family were informed consent.
Exclusion criteria
Exclusion criteria: 1. Respiratory infection, nervous system and cardiovascular diseases, impaired kidney or liver function; 2. Hypersensitivity to mivacurium and other anesthetic agents; 3. Neuromuscular and metabolic diseases; 4. Muscle relaxant administration during the previous 7 days, participation in any clinical subjects within the previous 30 days before the study, children who need to receive antibiotics that effect neuromuscular blocking agents (NMB); 5. Laryngeal mask placement times >= 3 and/or poor placement of laryngeal mask airway; 6. 20% deviation from ideal child body weight.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The onset time;duration of clinical action;duration of total action;recovery index; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;SpO2; | — |
Countries
China
Contacts
Public ContactXueping Han
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed