perioperative neurocognitive disorders
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Medical College of Shihezi University of Xinjiang
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Open surgery lasting =2 h; 2) Age 65-85; 3) Postoperative hospital stay =7 days; 4) ASA was graded ?-?.
Exclusion criteria
Exclusion criteria: 1) A history of neurosurgery or cardiac surgery;2) A history of central nervous system disease;3) Taking sedatives or antidepressants;4) Alcohol consumption =80 g pure alcohol/day ×10 years;5) Severe visual or hearing impairment, or other inability to communicate normally;6) Have been exposed to the same neuropsychological scale; 7) The Simple Intelligence Scale test (MMSE) meets the exclusion criteria: illiteracy < 18 points; Primary school < 21; Junior high school and above < 25;8) Refusing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination;Wechsler Adult Intelli-gence Scale-Fourth Edition; | — |
Secondary
| Measure | Time frame |
|---|---|
| malondialdehyde;Superoxide dismutase;umor necrosis factor alpha;Interleukin 1ß;Interleukin 6;Interleukin-10;euron specific enolase;Serum S-100ß protein; | — |
Countries
China
Contacts
Public ContactXie Liping
The First Affiliated Hospital of Medical College of Shihezi University of Xinjiang
Outcome results
None listed