Inflammatory arthritis
Conditions
Interventions
Suspicious RA group:Meridian-sinew release therapy
RA group:Meridian-sinew release therapy Method
SpA group:Meridian-sinew release therapy Method
OA group:Meridian-sinew release therapy Method
GA group:Meridian-sinew release therapy Method
Control group:Meridian-sinew release therapy Method
Sponsors
General Hospital of Southern Theatre Command
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Suspicious RA group: with similar clinical manifestations of RA, not reaching the 2010 American Society of Rheumatology (ACR) /The diagnostic criteria for RA developed by the European Union against Rheumatology (EULAR) exclude other diseases that can cause joint symptoms Disease, and serum RF, anti-CCP negative patients with suspected RA (including undifferentiated arthritis). RA group: patients who were definitely diagnosed as RA, all patients met the 2010 American Association of Rheumatology (ACR) /Diagnostic criteria for RA developed by the European Union against Rheumatology (EULAR). Spinal arthritis (SpA) group: all patients with inflammatory arthritis who were clearly diagnosed met the requirements of 2009 The diagnostic standard of axial SpA developed by the International Association for the Evaluation of Spinal Arthritis (ASAS) in 2011 or the international The diagnostic criteria for peripheral SpA developed by the Association for the Evaluation of Spinal Arthritis (ASAS), including ankylosing spondylitis Undifferentiated spinal arthritis, psoriatic arthritis, etc. Osteoarthritis (OA) group: all patients with non-inflammatory arthritis who were clearly diagnosed met the criteria of 2010 The diagnostic criteria for knee OA formulated by the "Guidelines for the Diagnosis and Treatment of Osteoarthritis" of the Branch of Bone Sciences of the Chinese Medical Association. Gouty arthritis (GA) group: in line with the diagnostic criteria for gout jointly formulated by ACR/EULAR in 2015 Of patients. Control group: patients with sports injury, trauma or rheumatic cold arthralgia who need or are willing to carry out local joint surgery Patients with ultra-minimally invasive treatment.
Exclusion criteria
Exclusion criteria: ? Have a serious history of infection in the last month; ? Patients with severe diseases of important organs such as respiratory system, cardiovascular system, digestive system, urinary system and blood system, as well as severe extra-articular manifestations such as constrictive pericarditis, vasculitis, secondary Sjogren's syndrome, etc. requiring glucocorticoids; ? Overlap syndrome with other rheumatic diseases; ? Patients with HIV infection and malignant tumor; ? Pregnant and lactating women, women with family planning and psychotic patients; ? Patients who are allergic to lidocaine or unable to undergo minimally invasive treatment; ? Does not meet the above diagnostic criteria; Patients without informed consent; Patients who may not be able to complete the whole process of this study; The researcher believes that this clinical trial is not suitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erythrocyte sedimentation rate;C-reactive protein;Serum uric acid;Inflammatory cytokines;High throughput sequencing;RF;ACPA;Knee joint synovial score under Needle-knife mirror ;Krenn score;Clinical signs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Infrared thermal imaging; Musculoskeletal ultrasound ;zxcv; | — |
Countries
China
Contacts
Public ContactShaowei Li
Department of Chinese Medicine and Rheumatology, General Hospital of Southern Theatre Command, Guangzhou, 510010, Guangdong, China
Outcome results
None listed