depressive disorder
Conditions
Interventions
Treament group:Treatment with EFFL Therapy Lamp, illuminance: 10000 lux
Control group:Treated with a placebo lamp, illumination: 900 lux
Sponsors
Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of mild to moderate depression in ICD-10; 2. Hamilton Depression Scale HAMD 17-item score between (inclusive) 17 and 25; 3. Aged 18-65 years, gender is not limited; 4. Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Organic brain lesions (such as cerebral hemorrhage, massive cerebral infarction, encephalitis, epilepsy); Cardiac QTc interval > 450ms; 2. Patients who are at serious risk of suicide or have attempted suicide; 3. Patients who are receiving other psychotherapy; 4. Pregnant, breastfeeding or planning pregnancy during the trial period; 5. Drug abusers; 6. Patients suffering from other unstable medical diseases; 7. Patients with retinopathy of any degree (including retinal diseases due to diabetes); 8. Those who have taken citalopram or received phototherapy within 30 days before the initial diagnosis; 9. Seriously ill patients, including those with heart, liver, kidney, respiratory, endocrine, nerve, blood and other diseases and not yet stable, and those with a history of convulsions; 10. Severe allergy and multiple adverse drug reactions; 11. Patients who regularly or currently take psychotropic drugs, including lithium, melatonin, and tryptophan; 12. Patients who have previously taken ß-blockers; 13. Patients with hypertension who are taking guanethidine, Reserpine, clonidine, or methyldopa (these medications may alter mood); 14. Patients who have taken any antidepressant drugs, such as monoamine oxidase inhibitors and heterocyclic antidepressants, within 30 days before their initial diagnosis;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton depression scale-17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index;Montgomery-Asberg depression rating scale;Self-rating depression scale;Clinical global impressions scale;Treatment emergent symptom scale;Morningness-eveningness questionnaire;Fatigue severity Scale;Sleep diary;Electrocardiogram;General demographic questionaire;Vital signs; | — |
Countries
China
Contacts
Public ContactBin Zhang
Nanfang Hospital, Southern Medical University
Outcome results
None listed