A multi-center clinical study on the treatment of knee osteoarthritis in early and middle stages by three steps and nine methods of whole knee

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068287

Enrollment

Unknown

Registered

2023-02-14

Start date

2023-02-07

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

treatment group:three steps and nine methods of whole knee

control group:warm type of low-frequency therapy

Eligibility

Sex/Gender

All

Age

40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients who met the Western diagnostic criteria and TCM syndrome differentiation criteria of knee osteoarthritis were classified as grade I-III; 2. Age 40-75 years old, gender is not limited; 3. No hormone or non-steroidal anti-inflammatory drugs were used in the first 3 months of enrollment, and no other relevant treatment was received; 4. Patients who have signed informed consent and guaranteed to complete the course of treatment.

Exclusion criteria

Exclusion criteria: 1. Patients who do not meet the diagnostic criteria of Western medicine and syndrome differentiation criteria of traditional Chinese medicine for knee osteoarthritis; 2. Women who are nursing or preparing for pregnancy; 3. Allergic constitution and multiple drug allergy; 4. Patients with severe primary diseases of liver, kidney, hematopoietic system, endocrine system, cardiovascular and cerebrovascular system, nervous system, tuberculosis, vertebral malformations, malignant tumors and mental diseases; Suspected history of sedative hypnosis, opioid analgesics and alcohol abuse; Patients with skin diseases and infectious diseases; 5. Patients in critical condition who should be treated with surgery; 6. Patients who should not or cannot use this treatment for other reasons; 7. There are mental disorders, language disorders, motor dysfunction, mental illness patients.

Design outcomes

Primary

Measure	Time frame
visual analogue scale score;WOMAC Osteoarthritis Index Questionnaire Survey;SF-36 score;Knee joint circumference;X-ray;	—

Countries

China

Contacts

Public ContactYe jie

Longhua Hospital, Shanghai University of Traditional Chinese Medicine

yejie1977@126.com+86 13301880301

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026