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The inhibitory effect of different doses of propofol on perineal itching caused by dexamethasone sodium phosphate

The inhibitory effect of different doses of propofol on perineal itching caused by dexamethasone sodium phosphate

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068283
Enrollment
Unknown
Registered
2023-02-13
Start date
2023-02-15
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

itching

Interventions

P1:0.1mg/kg propofol injection
P2:0.2mg/kg propofol injection
P3:0.3mg/kg propofol injection
P4:0.4mg/kg propofol injection
P5:0.5mg/kg propofol injection

Sponsors

Affiliated Hospital of Yangzhou University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years old; 2. ASA classification I-II grade; 3. Body mass index (BMI) 18-30kg/m2.

Exclusion criteria

Exclusion criteria: 1. Patients with paresthesia or pruritus; 2. Drug and alcohol abuse; 3. Allergies to lipid drugs and contraindications; corticosteroids are cautious; 4. Hyperlipidemia; 5. Patients during pregnancy and lactation; 6. Mental diseases, communication disorders; 7. Patients who use hormones for a long time.

Design outcomes

Primary

MeasureTime frame
Duration of itching;Incidence of itching;Severity of itching;visual analogue scale;Ramsay score;—

Countries

China

Contacts

Public ContactLiu Meiyu

Affiliated Hospital of Yangzhou University

meiyuliu@yzu.edu.cn+86 177 6198 0727

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026