Comparative study on the rehabilitation effects of intermittent blood flow restriction combined with low load resistance training and high load resistance training for PFPS patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068281

Enrollment

Unknown

Registered

2023-02-13

Start date

2023-02-13

Completion date

Unknown

Last updated

2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patellofemoral pain syndrome

Interventions

Intermittent blood flow restriction group:Intermittent blood flow restriction combine with low load resistance training

control group:High load resistance training

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) aged between 18 and 40; (2) experiencing 4 weeks but no more than 12 months of anterior knee pain, unilaterally or bilaterally (when bilateral, the side with the worse pain intensity, as assessed by Visual Analogue Scale (VAS), will be considered the affected leg); (3) symptoms not resulting from a traumatic injury; (4) pain present in any two of the following: running, jumping, squatting, kneeling, going up or down stairs, or prolonged sitting; and (5) displaying clinical examination findings consistent with PFP symptoms, includes the use of patellar tilt and squat as the gold standard tests,34 along with additional tests such as the apprehension test, patellar compression test, compression test, tenderness upon palpation of the posterior surface of the patella or surrounding structures, and resisted knee extension.

Exclusion criteria

Exclusion criteria: (1) history of patellar dislocation or subluxation, chondral damage, or ligament laxity; (2) suspicion of patellar tendinopathy, localized pain on patellar tendon and relieved pain during knee resisted extension; (3) previous knee surgery or arthritis; (4) an invasive procedure, such as arthroscopy or intra-articular injection, in the affected knee within the past 12 months; (5) participation in physical therapy or knee-strengthening exercises in the last 6 months; (6) usage of nonsteroidal anti-inflammatory drugs (NSAIDs) within the past 3 months; (7) presence of neurological, cardiovascular, or blood-related conditions; (8) abnormally high blood pressure (resting systolic blood pressure [SBP] > 140 or diastolic blood pressure [DBP] > 90 mmHg);35 (9) existing physical or cognitive conditions; (10) pregnancy.

Design outcomes

Primary

Measure	Time frame
Pain Score;Knee joint function;	—

Secondary

Measure	Time frame
Muscular strength;Muscle thickness;quality of life;	—

Countries

China

Contacts

Public ContactGuoxin Ni

Beijing Sport University

nigx@bsu.edu.cn+86 10 6298 9780

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026