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Effect of long duration of intraoperative infusion of norepinephrine on renal function and vital organ complications after abdominal surgery in elderly patients

Effect of long duration of intraoperative infusion of norepinephrine on renal function and vital organ complications after abdominal surgery in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068275
Enrollment
Unknown
Registered
2023-02-13
Start date
2023-02-15
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

abdominal tumor

Interventions

Group T:Norepinephrine was injected continuously during the operation
Group C:Unconventional use of vasopressor drugs. When hypotension occurs, a single intravenous injection of 0.3 mg Alamin

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification I-III; 2. Age 60-85 years; 3. Elective abdominal surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. The study protocol involved drug allergy; 2. Complicated with serious heart, liver, kidney, hematopoietic system diseases; 3. BMI 30 kg/m ^ 2 or more; 4. Patients with expected difficult airway; 5. Patients with contraindications to norepinephrine; 6. Bradycardia (heart rate < 50 beats/min).

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative acute kidney injury (stage 1 or above according to KDIGO criteria);—

Secondary

MeasureTime frame
Incidence of complications of vital organs within 30 days after surgery;Infection within 30 days after operation;—

Countries

China

Contacts

Public ContactCao Longhui

Sun Yat-Sen University Cancer Center

caolh@sysucc.org.cn+86 138 2609 2036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026