Effect of sodium supplementation according to urine sodium concentration on growth and development in very premature infants

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300068251

Enrollment

Unknown

Registered

2023-02-13

Start date

2023-02-13

Completion date

Unknown

Last updated

2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature infant nutrition

Interventions

Control group:Accept sodium supplementation based on general recommendations

Observation group:Accept sodium supplementation according to urine sodium concentration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Admitted to hospital within 24 hours after birth and gestational age of 23-32 weeks; 2. The family members of the children voluntarily joined and cooperated with the study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Birth weight > 1500g; 2. With severe congenital malformation, chromosome abnormality, renal insufficiency (increase of serum creatinine >= 0.5 mg/dL/d, urine volume < 0.5 mL/kg/h) or disease status characterized by edema; 3. Underwent enterostomy due to necrotizing enterocolitis within 3 days after birth; 4. Blood sodium concentration on the 4th day after birth is outside the range of 130-150 mmol/L.

Design outcomes

Primary

Measure	Time frame
weight;Length;Head circumference;Infant motor performance test;	—

Countries

China

Contacts

Public ContactLiufang He

People's Hospital of Longhua Shenzhen

heliufang6022@163.com+86 189 3869 0179

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026