horizontal bone defect in the anterior region (Class IV by Cawood-Howell, Type 1/4 or Type 2/4 by Terheyden)
Conditions
Interventions
L-shape Bio-Oss Collagen group (test group):A L-Shape Technology will be used in the test group, the Geistlich Bio-Oss Collagen will be trimmed as a L shape to put on the top of Geistlich Bio-Oss with
GBR group (control group):Guided bone regeneration with Bio-Oss and Bio-Gide
Sponsors
School and Hospital of Stomatology, Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. With favorable type of horizontal bone defect (Class IV by Cawood-Howell, Type 1/4 or Type 2/4 by Terheyden) who have been missing the tooth for more than 3 months and need horizontal bone augmentation and implant restoration; 3. Bone defect involving a single tooth in the anterior region; 4. No history of bisphosphonate use.
Exclusion criteria
Exclusion criteria: 1. With cardiovascular and cerebrovascular-related systemic diseases who cannot tolerate surgery; 2. Heavy smokers (>= 20 cigarettes/day); 3. With psychiatric diseases; 4. Pregnant and lactating women; 5. With acute inflammation of adjacent teeth or uncontrollable periodontal diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of horizontal bone thickness at the lines perpendicular to the implant's long axis at the implant shoulder (HT0) of the augmented region via CBCT images; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of HT2 (the lines perpendicular to the implant's long axis at 2mm below the shoulder) of the augmented regions;Change of HT4 (the lines perpendicular to the implant's long axis at 4mm below the shoulder) of the augmented regions;Vertical thickness (VT, following the long axis of the coronal portion of the implant);45° vertical thickness (45-VT, at a 45° positive angle relative to the long axis of the coronal portion of the implant);Early postoperative discomfort and wound healing;Implant Stability of the augmented sites via PTV value;PES and WES; | — |
Countries
China
Contacts
Public ContactJing Lan
Shandong University / School and Hospital of Stomatology, Shandong University
Outcome results
None listed