A multi-center clinical study on the reconstruction of finger extensor function by transposition of the supinator branch to repair the posterior interosseous nerve

A study on the regulation of peripheral nerves in central limb spastic paralysis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068214

Enrollment

Unknown

Registered

2023-02-10

Start date

2023-02-15

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central spastic paralysis of upper limbs

Interventions

group 1:T1 nerve root rhizotomy + supinator branch repair posterior interosseous nerve + rehabilitation therapy

group 2:T1 nerve root rhizotomy operation + rehabilitation therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 3-60 years old; 2. The history of central spastic paralysis of upper limbs caused by brain trauma and stroke was >= 1 year, and the history of cerebral palsy was >= 3 years; 3. Modified Ashworth Scale hand flexor muscle tone >= 2 and elbow flexor muscle tone = 3, finger extensor muscle strength = 3; 5. All joints of the upper limbs had no contracture and fixed stiffness deformity.

Exclusion criteria

Exclusion criteria: 1. Athetosis; 2. Hypertonia due to extrapyramidal system and other lesions; 3. Mental retardation; 4. History of neurotomy.

Design outcomes

Primary

Measure	Time frame
Flexor tone of hand (Modified Ashworth scale);	—

Secondary

Measure	Time frame
Fugl-Meyer upper limb function score;Modified House Functional Classification;Muscle strength (MRC grade);	—

Countries

China

Contacts

Public ContactWenjun Li

Beijing Jishuitan Hospital

dcliwenjun@163.com+86 139 1045 2661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026