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Optimization of perioperative pulmonary function in children with individualized PEEP by EIT titration

EIT was used to guide ventilation strategy during general anesthesia and improve perioperative pulmonary function in children

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068208
Enrollment
Unknown
Registered
2023-02-10
Start date
2023-02-12
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative Atelectasis

Interventions

experimental group:Individual PEEP titration under the guidance of EIT was performed on intraoperative ventilation in the experimental group, and atelectasis was evaluated and scored by lung ultrasoun
control group:The control group was given fixed peep of 5cmH2O during intraoperative ventilation. Atelectasis was evaluated and scored by lung ultrasound after intubation(T1), after surgery(T2), and 1

Sponsors

Xinhua Hospital Affilliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. ASAI-II, children who are about to undergo laparoscopic surgery; 2. Informed consent was obtained from patients or their family members.

Exclusion criteria

Exclusion criteria: 1. Patients with hemodynamic instability; 2. Patients with abdominal distension or obvious lung, heart or chest wall disease; 3. Obese or overweight children; 4. The operation time is more than 2 hours.

Design outcomes

Primary

MeasureTime frame
Atelectasis ultrasound score (LUS);

Secondary

MeasureTime frame
Incidence of atelectasis in children assessed by lung ultrasound after intubation (T1) and one hour after surgery (T3);Lung compliance;Respiratory mechanical index (airway resistance, airway plateau pressure, peak pressure, pressure equalization);blood pressure;Heart Rate;SpO2;Incidence of hemodynamic unstable events;Incidence of postoperative airway adverse events;Length of stay;

Countries

China

Contacts

Public ContactWang Shenghua

Xinhua Hospital Affilliated to Shanghai Jiao Tong University School of Medicine

Subatsil@163.com+86 15509380019

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026