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A multi-center clinical study on the reconstruction of finger flexor function by transposition of C7 nerve on the uninjured side to repair T1 nerve root

A study on the regulation of peripheral nerves in central limb spastic paralysis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300068191
Enrollment
Unknown
Registered
2023-02-09
Start date
2023-02-15
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central spastic paralysis of upper limbs

Interventions

T1 nerve root rhizotomy+uninjured side C7 repair T1+rehabilitation group :T1 nerve root rhizotomy+uninjured side C7 repair T1+rehabilitation therapy

Sponsors

Beijing Jishuitan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 3-60 years; 2. The history of central spastic paralysis of upper limbs caused by brain trauma and stroke was >=1 year, and the history of cerebral palsy was >=3 years; 3. Modified Ashworth Scale hand flexor muscle tone >=2; 4. All joints of the upper limbs had no contracture and fixed stiffness deformity.

Exclusion criteria

Exclusion criteria: 1. Athetosis; 2. Hypertonia due to extrapyramidal system and other lesions; 3. Mental retardation; 4. History of neurotomy; 5. MRC grade finger flexor muscle strength >=3; 6. Extensor finger and elbow strength <4 in MRC grade on the healthy side.

Design outcomes

Primary

MeasureTime frame
Flexor tone of hand (Modified Ashworth scale);

Secondary

MeasureTime frame
Fugl-Meyer upper limb function score;Modified House functional classification;Muscle strength (MRC grade);

Countries

China

Contacts

Public ContactLi Wenjun

Beijing Jishuitan Hospital

dcliwenjun@163.com+86 139 1045 2661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026