cardiopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with ASA?-? grade, age 18-75 years old, height 155-175cm, who are scheduled to undergo cardiac and large vessel surgery (including coronary artery bypass grafting, valve replacement or plasty, large vessel surgery and congenital heart disease correction, as well as multiple surgical combined operations among the above four types of surgery) under general anesthesia and CPB. Body weight 45 ~ 75kg, BMI18 ~ 32kg/m2, approved by the ethics committee of the hospital, voluntary entry, signed the informed consent.
Exclusion criteria
Exclusion criteria: Pheochromocytoma and primary aldosteronism; Patients receiving a large amount of catecholamines before surgery; Patients with malignant arrhythmia before anesthesia induction after entering the operating room; Patients with non-sinus rhythm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ambulatory blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| adrenaline in serum ;norepinephrine in serum ;Left ventricular ejection fraction;Mechanical ventilation time;ICU care time; | — |
Countries
China
Contacts
Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen