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Changes in the length of umbilical cord blood telomeres in offspring of patients with gestational diabetes mellitus and its related mechanism

Changes in the length of umbilical cord blood telomeres in offspring of patients with gestational diabetes mellitus and its related mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300068159
Enrollment
Unknown
Registered
2023-02-09
Start date
2023-02-04
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes

Interventions

gestational diabetes mellitus group:No
non-gestational diabetes mellitus group:No

Sponsors

Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 30 Years

Inclusion criteria

Inclusion criteria: Study group: age 25-30 years, gestational age 39-41 weeks, vaginal or cesarean delivery, control group: no pregnancy complications, age 25-30 years, gestational age 39-41 weeks, spontaneous or cesarean delivery.

Exclusion criteria

Exclusion criteria: These include multiple pregnancies, preconceptional diabetes, hypertensive disorders during pregnancy, infectious diseases detected during pregnancy, intrahepatic cholestasis during pregnancy, recurrent bleeding during pregnancy, placenta previa, placental abruption, emergency labor, oligo/too much hydramnios, and complicated medical complications.

Design outcomes

Primary

MeasureTime frame
Telomere length;Telomerase methylation status;—

Secondary

MeasureTime frame
Telomerase activity;Telomerase activity;Telomere damage status;Telomel protein expression;—

Countries

China

Contacts

Public ContactShuhua Liu

Anhui Medical University/ Anhui Province Maternity and Child Health Hospital

liushuhua0225@163.com15256030049

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026