A randomized controlled clinical study of T1 nerve root rhizotomy for the relief of hand flexor muscle spasm

A study on the regulation of peripheral nerves in central limb spastic paralysis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300068143

Enrollment

Unknown

Registered

2023-02-08

Start date

2023-02-15

Completion date

Unknown

Last updated

2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central spastic paralysis of upper limbs

Interventions

T1 nerve root rhizotomy+rehabilitation group:T1 nerve root rhizotomy operation+rehabilitation therapy

rehabilitation group:rehabilitation therapy

Eligibility

Sex/Gender

All

Age

3 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 3 ~ 60 years; 2. History of central upper limb spasm paralysis caused by brain trauma and stroke >=1 year, cerebral palsy >=3 years; 3. Improved Ashworth grade flexor finger muscle tension >= level 2; 4. No contracture or fixed stiffness deformity in the joints of the upper limbs.

Exclusion criteria

Exclusion criteria: 1. Athetosis; 2. Hypertonia due to extrapyramidal system and other lesions; 3. Mental retardation; 4. History of neurotomy.

Design outcomes

Primary

Measure	Time frame
Flexor tone of hand (Modified Ashworth Scale);	—

Secondary

Measure	Time frame
Fugl-Meyer upper limb function score;Modified House functional classification;Muscle strength (MRC grade);	—

Countries

China

Contacts

Public ContactLi Wenjun

Beijing Jishuitan Hospital

dcliwenjun@163.com+86 139 1045 2661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026